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Symbol
Name
ID
Stat6
signal transducer and activator of transcription 6
MGI:103034
Phenotype annotations related to hematopoietic system
Darker colors indicate more annotations

Mouse Phenotypes
increased B cell apoptosis
impaired eosinophil chemotaxis
impaired neutrophil chemotaxis
abnormal leukocyte migration
abnormal B cell proliferation
decreased B cell proliferation
decreased T cell proliferation
abnormal class switch recombination
abnormal CD4-positive T cell differentiation
abnormal T-helper 1 cell differentiation
abnormal T-helper 2 cell differentiation
abnormal mast cell morphology
decreased T-helper 2 cell number
abnormal CD8-positive, alpha beta T cell morphology
abnormal leukocyte physiology
abnormal granulocyte physiology
impaired eosinophil recruitment
abnormal B cell physiology
abnormal immunoglobulin level
decreased IgA level
increased IgA level
decreased IgE level
increased IgE level
decreased IgG1 level
increased IgG1 level
increased IgG2a level
decreased IgG3 level
increased IgG level
decreased IgM level
abnormal T-helper 2 physiology
abnormal cytotoxic T cell physiology
abnormal macrophage physiology
Availability Mouse Genotype
Stat6tm1Aki/Stat6tm1Aki
Stat6tm1Gru/Stat6tm1Gru
Stat6tm1Jni/Stat6tm1Jni

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory